Hi,
Yes Hraban it works outside in normal text flow. When I do e.g. {\InitialCapFont
test in normal text flow} the text 'test in normal text
flow' is rendered correctly in the Antykwa-Poltawskiego
font.
Found out that the following does work with the \placeinitial command:
\setupinitial[color=MyColor,distance=6pt,n=3,font=name:antpoltcondregular*default
sa 4]