I eventually got it to work as following:

\definefloat
  [figure]

\setupcaption
  [figure]
  [style=italic]


Op za 10 mei 2025 om 13:17 schreef Wolfgang Schuster <wolfgang.schuster.lists@gmail.com>:
Am 10.05.2025 um 12:58 schrieb Jeroen:
> Is there an easy way to change the capture below all figure captures to
> italic?

Use

   \setupcaption [figure] [style=italic]

to change the style of \placefigure only or use

   \setupcaption [style=italic]

to change the style of all floats, i.e. \placefigure, \placetable etc.

Wolfgang

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