Pablo Rodriguez
12. August 2016 um 17:21
Interline spacing is set in an unorthodox way (to put it fine), but
there is no "setups" key for \setupparagraphs (or it doesn’t work).

Let us know whether you find more issues.
You can apply setups with the inner key:

\defineparagraphs[TwoColumns][n=2,align=verytolerant]

\startsetups[TwoColumns]
  \setupinterlinespace[line=5ex]
\stopsetups

\setupparagraphs[TwoColumns:2][inner=\directsetup{TwoColumns}]

\starttext

\startTwoColumns
\input knuth
\TwoColumns
\input tufte
\stopTwoColumns

\stoptext

Wolfgang