[NTG-context] Multiple Search/Replace in one script?

Hi, I am looking for a way to automate (and also archive) my most common ten or twenty search/replace runs. I have to admit, I have no idea about scripting. But I guess there should be a way in Applecript/Perl/Rupy/Whatever to write down several entries with... ... what should be the search string ... what should be the replace string ... what kind of search should be opeated (regulr expression, case sensitive, etc.) Any recommendations? Steffen