I have a document that uses ~40 different TABLE configurations, each with their own special requirements, such as these below, and in total, perhaps 2000 tables appear in a file, using one of the configurations.
\setupTABLE[r][1][align=raggedleft]
\setupTABLE[c][1][width=.1\textwidth]
\setupTABLE[c][2][width=.33\textwidth]
\setupTABLE[c][3][width=.37\textwidth]
\setupTABLE[c][4][width=.1\textwidth]
\setupTABLE[c][5][width=.1\textwidth]
\setupTABLE[c][1,2,3,4,5][align=raggedleft, frame=off]
%\setupTABLE[r][2,3,4,5,6,8,9,11,12,14][bottomframe=off]
\setupTABLE[r][1][bottomframe=on]
\bTABLE[split=yes]
\bTR\bTD {\it Lesson} \eTD\bTD {\it Time} \\eTD\bTD {\it Date} \eTD\bTD {\it Page} \eTD\eTR
\eTABLE
What I've been finding is that previous settings on TABLES appearing earlier in the document is impacting later tables. For instance, if one has a frame to the right of column 1, then the next table seems to acquire this setting as well, even if it isn't expected to have any frames at all.
Note that each unique table is defined inside a macro.